Saliva is NOT lube. It might seem convenient, but it dries up quickly, increases friction, and can actually make things more uncomfortable. Plus, it can carry bacteria and infections that you don't Can your lube affect your chances of getting pregnant? Yes some lubricants can make it harder for sperm to reach the egg. Look for sperm safe or fertility friendly formulas that mimic your Cervical Mucus and Fertile Window: How Sperm Friendly Lubricants Help Home Insemination Solutions ZA The most pregnancy friendly lubricants are the water based kinds. These lubes are water soluble, which means they dissolve in water. They're safer for you and your baby, typically because they contain fewer chemicals than Lubricant Glow Community Fertility Lubricant, 9 Applicators, 1.4 oz (40 g)